Comparison of Antioxidant and Ant proliferative Effect among Four Passiflora Spp.
Talita Cristina Colomeu, Daniella de Figueiredo, Ricardo de Lima Zollner, Laura Maria Molina Meletti
Abstract
In the last years, increased the studies with phenolic compounds in the development of new natural drugs. The choice of solvent/method for extraction of phenolic compounds is crucial. The extraction of phenolic compounds with the solvents water, ethanol and methanol/acetone were used. The evaluation of the antioxidant capacity (DPPH;FRAP ;ABTS) and total phenolic was analysed in the four species of Pass flora. The inhibition cellular and apoptosis/necrosis analysis were studied on T lymphocytes after treatment with yellow P.edulis, purple P.edulis, P.alata and P.quadrangularis. Water was considered the best solvent to extract phenolic compounds. The yellow P.edulis was higher antioxidant activity. Already, the analysis of cell inhibition and apoptosis/necrosis on T lymphocytes showed that aqueous extract of P.alata has the highest ant proliferative effect. The results showed that different solvents can have different extraction efficiency of phenol compounds, antioxidant activity and cell activity, demonstrating the importance of a correct choice of extraction method.
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