Mini Review Study of Antitubercular Drugs of Nicotinamide, Thioisonicotinamide and Pyrazinamide Derivatives
Mohammad Asif
Abstract
The tuberculosis is a typically chronic infection caused by Mycobacterium tuberculosis. The progress of effective
treatment of tuberculosis (TB) has been recently due to alarm regarding the appearance of vastly drug-resistant
TB strains. The efforts that gave rise to current first line and second-line anti-TB drugs in global use today and
attempts to summarize ongoing discovery being conducted. The TB has different disease-specific concerns and
control that introduce major complexity in drug discovery efforts. In this article a brief discussion about
nicotinamide, thioisonicotinamide and pyrazinamide analogues for the better and effect TB treatment particular
against resistance mycobacterium strains.
Full Text: PDF